1 Frid A. H., Hirsch L. J., Menchior A. R., Morel D. R., Strauss K. W. Worldwide injection technique questionnaire study: injecting complications and the role of the professional. Mayo Clinic Proceedings . 2016;91(9):1224–1230. doi: 10.1016/j.mayocp.2016.06.012.
2 Blanco M, Hernández MT, Strauss KW, Amaya M. Prevalence and risk factors of lipohypertrophy in insulin-injecting patients with diabetes. Diabetes Metab. 2013;39(5):445-453. doi:10.1016/j.diabet.2013.05.006
* From February 1, 2014, through June 30, 2015, 13,289 insulin-injecting patients from 423 centers in 42 countries took part in one of the largest surveys ever performed in diabetes. The threshold for staying in the model was P<.05. Two-tailed tests were used in all the analyses.Ş Multicentre randomized study in Spain. Evaluation performed on 430 patients including 47 children and 383 adults. 177 (41%) had T1D and 253 (59%) had type 2 diabetes (T2D). 39.1% of patients with LH had hypoglycaemia and 49.1% had glycaemic variability compared with only 5.9% and 6.5%, respectively, in those without LH (both P < 0.01).