| Synthesis and Pro-Apoptotic Effects of Nitrovinylanthracenes and Related Compounds in Chronic Lymphocytic Leukaemia (CLL) and Burkitt’s Lymphoma AJ Byrne, SA Bright, JP McKeown, A Bergin, B Twamley, AM McElligott, ... Molecules 28 (24), 8095, 2023 | | 2023 |
| Synthesis and biological evaluation of 2-azetidinone derivatives with antiproliferative activity in breast cancer and chemoresistant colon cancer AM Malebari, B Twamleyb, D Fayne, MJ Meegan MDPI, 2023 | | 2023 |
| Targeting conserved protein binding sites on SARS-CoV-2: nsp3 case study S Kandwal, D Fayne MDPI, 2023 | | 2023 |
| DataPype: A Fully Automated Unified Software Platform for Computer-Aided Drug Design MF Khan, S Kandwal, D Fayne ACS omega 8 (42), 39468-39480, 2023 | 2 | 2023 |
| Antiproliferative and Tubulin-Destabilising Effects of 3-(Prop-1-en-2-yl) azetidin-2-Ones and Related Compounds in MCF-7 and MDA-MB-231 Breast Cancer Cells S Wang, AM Malebari, TF Greene, S Kandwal, D Fayne, SM Nathwani, ... Pharmaceuticals 16 (7), 1000, 2023 | 1 | 2023 |
| Genetic conservation across SARS-CoV-2 non-structural proteins–Insights into possible targets for treatment of future viral outbreaks S Kandwal, D Fayne Virology, 2023 | 4 | 2023 |
| Mapping of Protein Binding Sites using clustering algorithms-Development of a pharmacophore based drug discovery tool J Braun, D Fayne Journal of Molecular Graphics and Modelling 115, 108228, 2022 | 5 | 2022 |
| Synthesis, characterisation and mechanism of action of anticancer 3-fluoroazetidin-2-ones AM Malebari, G Duffy Morales, B Twamley, D Fayne, MF Khan, ... Pharmaceuticals 15 (9), 1044, 2022 | 4 | 2022 |
| Repurposing drugs for treatment of SARS-CoV-2 infection: computational design insights into mechanisms of action S Kandwal, D Fayne Journal of Biomolecular Structure and Dynamics 40 (3), 1316-1330, 2022 | 20 | 2022 |
| Synthesis and antiproliferative evaluation of 3-chloroazetidin-2-ones with antimitotic activity: Heterocyclic bridged analogues of combretastatin a-4 AM Malebari, S Wang, TF Greene, NM O’boyle, D Fayne, MF Khan, ... Pharmaceuticals 14 (11), 1119, 2021 | 11 | 2021 |
| Synthesis and Biological Evaluation of 1-(Diarylmethyl)-1H-1,2,4-triazoles and 1-(Diarylmethyl)-1H-imidazoles as a Novel Class of Anti-Mitotic Agent for Activity in … G Ana, PM Kelly, AM Malebari, S Noorani, SM Nathwani, B Twamley, ... Pharmaceuticals 14 (2), 169, 2021 | 7 | 2021 |
| Synthesis, anti-proliferative activity, and molecular docking study of new series of 1, 3-5-triazine Schiff base derivatives HH Al Rasheed, AM Malebari, KA Dahlous, D Fayne, A El-Faham Molecules 25 (18), 4065, 2020 | 15 | 2020 |
| β-Lactams with antiproliferative and antiapoptotic activity in breast and chemoresistant colon cancer cells AM Malebari, D Fayne, SM Nathwani, F O’Connell, S Noorani, B Twamley, ... European journal of medicinal chemistry 189, 112050, 2020 | 33 | 2020 |
| Design, synthesis and biochemical evaluation of novel ethanoanthracenes and related compounds to target Burkitt’s lymphoma AJ Byrne, SA Bright, JP McKeown, JE O’Brien, B Twamley, D Fayne, ... Pharmaceuticals 13 (1), 16, 2020 | 8 | 2020 |
| 3-vinylazetidin-2-ones: Synthesis, antiproliferative and tubulin destabilizing activity in MCF-7 and MDA-MB-231 breast cancer cells S Wang, AM Malebari, TF Greene, NM O’boyle, D Fayne, SM Nathwani, ... Pharmaceuticals 12 (2), 56, 2019 | 13 | 2019 |
| Synthesis and evaluation of antiproliferative microtubule-destabilising combretastatin A-4 piperazine conjugates NM O'Boyle, G Ana, PM Kelly, SM Nathwani, S Noorani, D Fayne, ... Organic & Biomolecular Chemistry 17 (25), 6184-6200, 2019 | 18 | 2019 |
| Single point mutations reveal amino acid residues important for Chromobacterium violaceum transaminase activity in the production of unnatural amino acids SA Almahboub, T Narancic, D Fayne, KE O’Connor Scientific Reports 8 (1), 17397, 2018 | 7 | 2018 |
| Synthesis, antiproliferative and pro-apoptotic effects of nitrostyrenes and related compounds in Burkitt's lymphoma AJ Byrne, SA Bright, D Fayne, JP McKeown, T McCabe, B Twamley, ... Medicinal Chemistry 14 (2), 181-199, 2018 | 5 | 2018 |
| Lead optimization of benzoxepin-type selective estrogen receptor (ER) modulators and downregulators with subtype-specific ERα and ERβ activity NM O’Boyle, I Barrett, LM Greene, M Carr, D Fayne, B Twamley, AJS Knox, ... Journal of medicinal chemistry 61 (2), 514-534, 2018 | 38 | 2018 |
| Novel selective estrogen receptor ligand conjugates incorporating endoxifen-combretastatin and cyclofenil-combretastatin hybrid scaffolds: Synthesis and biochemical evaluation PM Kelly, NO Keely, SA Bright, B Yassin, G Ana, D Fayne, DM Zisterer, ... Molecules 22 (9), 1440, 2017 | 35 | 2017 |
